COMPOSITIONS COMPRISING ADDL RECEPTORS, RELATED COMPOSITIONS, AND RELATED METHODS
Disclosed and claimed herein are compositions comprising ADDL receptors, related compositions, and related methods. ADDL receptors are typically, but perhaps not exclusively, localized at the post-synaptic density (PSD) of neuronal cells. Related compositions include, but are not limited to, compoun...
Saved in:
Main Authors | , , , , , , , , , , , , , , |
---|---|
Format | Patent |
Language | English French |
Published |
24.11.2005
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Disclosed and claimed herein are compositions comprising ADDL receptors, related compositions, and related methods. ADDL receptors are typically, but perhaps not exclusively, localized at the post-synaptic density (PSD) of neuronal cells. Related compositions include, but are not limited to, compounds that affect, positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Related methods include, but are not limited to, procedures to screen for compounds that affect, either positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Other related methods include, but are not limited to, prevention and treatment of ADDL-related diseases, such as Alzheimer's disease, mild cognitive impairment, Down's syndrome, and the like, using compositions that inhibit, block, or otherwise interfere with ADDL binding to one or more receptors localized at the post-synaptic density of neuronal cells.
L'invention concerne des compositions contenant des récepteurs d'ADDL, ainsi que des compositions et des méthodes associées. Les récepteurs d'ADDL sont généralement, mais pas exclusivement, localisés au niveau de la densité postsynaptique (PSD) des cellules neuronales. Les compositions associées contiennent, entre autres, des composés qui modifient, positivement ou négativement, la liaison des ADDL aux cellules neuronales, soit par l'intermédiaire d'au moins un récepteur localisé au niveau de la densité postsynaptique (PSD) soit autrement. Les méthodes associées comprennent, entre autres, des procédures de criblage de composés qui modifient, soit positivement soit négativement, la liaison des ADDL aux cellules neuronales, soit par l'intermédiaire d'au moins un récepteur localisé au niveau de la densité postsynaptique (PSD) soit autrement. D'autres méthodes associées comprennent, entre autres, la prévention et le traitement de maladies liées aux ADDL, telles que la maladie d'Alzheimer, la déficience cognitive légère, le syndrome de Down et analogues, au moyen de compositions inhibant, bloquant ou entravant d'une autre manière la liaison des ADDL à au moins un récepteur localisé au niveau de la densité postsynaptique des cellules neuronales. |
---|---|
AbstractList | Disclosed and claimed herein are compositions comprising ADDL receptors, related compositions, and related methods. ADDL receptors are typically, but perhaps not exclusively, localized at the post-synaptic density (PSD) of neuronal cells. Related compositions include, but are not limited to, compounds that affect, positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Related methods include, but are not limited to, procedures to screen for compounds that affect, either positively or negatively, ADDL binding to neuronal cells, either via one or more receptors localized at the post-synaptic density (PSD) or otherwise. Other related methods include, but are not limited to, prevention and treatment of ADDL-related diseases, such as Alzheimer's disease, mild cognitive impairment, Down's syndrome, and the like, using compositions that inhibit, block, or otherwise interfere with ADDL binding to one or more receptors localized at the post-synaptic density of neuronal cells.
L'invention concerne des compositions contenant des récepteurs d'ADDL, ainsi que des compositions et des méthodes associées. Les récepteurs d'ADDL sont généralement, mais pas exclusivement, localisés au niveau de la densité postsynaptique (PSD) des cellules neuronales. Les compositions associées contiennent, entre autres, des composés qui modifient, positivement ou négativement, la liaison des ADDL aux cellules neuronales, soit par l'intermédiaire d'au moins un récepteur localisé au niveau de la densité postsynaptique (PSD) soit autrement. Les méthodes associées comprennent, entre autres, des procédures de criblage de composés qui modifient, soit positivement soit négativement, la liaison des ADDL aux cellules neuronales, soit par l'intermédiaire d'au moins un récepteur localisé au niveau de la densité postsynaptique (PSD) soit autrement. D'autres méthodes associées comprennent, entre autres, la prévention et le traitement de maladies liées aux ADDL, telles que la maladie d'Alzheimer, la déficience cognitive légère, le syndrome de Down et analogues, au moyen de compositions inhibant, bloquant ou entravant d'une autre manière la liaison des ADDL à au moins un récepteur localisé au niveau de la densité postsynaptique des cellules neuronales. |
Author | GONG, YUESONG LOWE, RAY VELASCO, PAULINE, T KLEIN, WILLIAM, L FERNANDEZ, SARA, J CHANG, LEI LAMBERT, MARY, P JERECIC, JASNA VIOLA, KIRSTEN, L CATALANO, SUSAN LACOR, PASCALE, N BUNIEL, MARIA, C PRAY, TODD KRAFFT, GRANT, A BIGIO, EILEEN, H |
Author_xml | – fullname: LACOR, PASCALE, N – fullname: LOWE, RAY – fullname: GONG, YUESONG – fullname: KLEIN, WILLIAM, L – fullname: KRAFFT, GRANT, A – fullname: CHANG, LEI – fullname: VELASCO, PAULINE, T – fullname: BIGIO, EILEEN, H – fullname: BUNIEL, MARIA, C – fullname: PRAY, TODD – fullname: FERNANDEZ, SARA, J – fullname: LAMBERT, MARY, P – fullname: CATALANO, SUSAN – fullname: VIOLA, KIRSTEN, L – fullname: JERECIC, JASNA |
BookMark | eNrjYmDJy89L5WQIdPb3DfAP9gzx9PcLVgBxgjyDPf3cFRxdXHwUglydXQNC_IOCdYBMH8cQVxcFZPU6Co5-LnAZX9cQD3-XYB4G1rTEnOJUXijNzaDs5hri7KGbWpAfn1pckJicmpdaEh_ub2RgYGpoCCTMHI2MiVMFAMDLMiY |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
DocumentTitleAlternate | COMPOSITIONS CONTENANT DES RECEPTEURS D'ADDL, COMPOSITIONS ET METHODES ASSOCIEES |
ExternalDocumentID | WO2005110056A2 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_WO2005110056A23 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 16:00:06 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English French |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_WO2005110056A23 |
Notes | Application Number: WO2005US17176 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20051124&DB=EPODOC&CC=WO&NR=2005110056A2 |
ParticipantIDs | epo_espacenet_WO2005110056A2 |
PublicationCentury | 2000 |
PublicationDate | 20051124 |
PublicationDateYYYYMMDD | 2005-11-24 |
PublicationDate_xml | – month: 11 year: 2005 text: 20051124 day: 24 |
PublicationDecade | 2000 |
PublicationYear | 2005 |
RelatedCompanies | GONG, YUESONG LOWE, RAY VELASCO, PAULINE, T KLEIN, WILLIAM, L ACUMEN PHARMACEUTICALS FERNANDEZ, SARA, J CHANG, LEI LAMBERT, MARY, P JERECIC, JASNA VIOLA, KIRSTEN, L NORTHWESTERN UNIVERSITY CATALANO, SUSAN LACOR, PASCALE, N BUNIEL, MARIA, C PRAY, TODD KRAFFT, GRANT, A BIGIO, EILEEN, H |
RelatedCompanies_xml | – name: KLEIN, WILLIAM, L – name: FERNANDEZ, SARA, J – name: KRAFFT, GRANT, A – name: VIOLA, KIRSTEN, L – name: BIGIO, EILEEN, H – name: BUNIEL, MARIA, C – name: LOWE, RAY – name: GONG, YUESONG – name: JERECIC, JASNA – name: VELASCO, PAULINE, T – name: CATALANO, SUSAN – name: ACUMEN PHARMACEUTICALS – name: LAMBERT, MARY, P – name: CHANG, LEI – name: PRAY, TODD – name: NORTHWESTERN UNIVERSITY – name: LACOR, PASCALE, N |
Score | 2.6372364 |
Snippet | Disclosed and claimed herein are compositions comprising ADDL receptors, related compositions, and related methods. ADDL receptors are typically, but perhaps... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | COMPOSITIONS COMPRISING ADDL RECEPTORS, RELATED COMPOSITIONS, AND RELATED METHODS |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20051124&DB=EPODOC&locale=&CC=WO&NR=2005110056A2 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1RT8IwEL4QNOqbokYUTRPNnlhkbEV5IAbazc24dW5TeSMDSmJiBpEZ_77XOZAn3tpe07SX3PW-tvcV4KaN7hCj6JneMmcd3UrbpjpoutMN2aIpnY4pNVU2sh903FfraUiHFfhc5cIUPKE_BTkiWtQE7T0v_PXi_xCLF28rl7fjD2yaPzhJj2srdKzCB0vjg54dCi6YxhjiNi2ISpkivuyjw95RgbRi2rffBiovZbG5qTiHsBvieFl-BBWZ1WCfrf5eq8GeX155Y7G0vuUxvDDhhyL2isxfoiqRF3vBI-lz_kwim9lhIqK4SdQ_GOiRyGb_JukHfC3x7cQVPD6Ba8dOmKvj3EZrVYzexeZCzFOoZvNMngExjAm976aIn1oIuKYm9jdlV-HPlFpyKuvQ2DbS-XbxBRz8UZYaettqQDX_-paXuBnn46tCh7_wL4UD |
link.rule.ids | 230,309,786,891,25594,76903 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT8IwEL8QNOKbosYP1CaaPbHI2AryQAy0w03Zh9tU3siAkpiYQWTGf99rBeSJt7bXNO0ld-2v7e8O4LaO7hBP0VO9Zk4bupXWTXnR1NQNUaMpnYwoNSUb2fMbzqv1NKCDAnyuuDAqTuiPCo6IFjVGe8-Vv57_X2Jx9bdycTf6wKbZQy9pc22FjuXxwdJ4t22HAQ-YxhjiNs2PljIZ-LKDDnuniaBQgaW3ruSlzDc3ld4B7IY4XpYfQkFkZSixVe61Mux5yydvLC6tb3EELyzwwiB2FfOXyErkxq7_SDqc90lkMztMgiiuEpkHAz0S2exfJR2fryWenTgBj4_hpmcnzNFxbsO1KobvweZCzBMoZrNMnAIxjDG9b6WIn2oIuCYm9jdFS-LPlFpiIs6gsm2k8-3iayg5idcf9l3_-QL2_8KXGnrdqkAx__oWl7gx56Mrpc9fTaSH7Q |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=COMPOSITIONS+COMPRISING+ADDL+RECEPTORS%2C+RELATED+COMPOSITIONS%2C+AND+RELATED+METHODS&rft.inventor=LACOR%2C+PASCALE%2C+N&rft.inventor=LOWE%2C+RAY&rft.inventor=GONG%2C+YUESONG&rft.inventor=KLEIN%2C+WILLIAM%2C+L&rft.inventor=KRAFFT%2C+GRANT%2C+A&rft.inventor=CHANG%2C+LEI&rft.inventor=VELASCO%2C+PAULINE%2C+T&rft.inventor=BIGIO%2C+EILEEN%2C+H&rft.inventor=BUNIEL%2C+MARIA%2C+C&rft.inventor=PRAY%2C+TODD&rft.inventor=FERNANDEZ%2C+SARA%2C+J&rft.inventor=LAMBERT%2C+MARY%2C+P&rft.inventor=CATALANO%2C+SUSAN&rft.inventor=VIOLA%2C+KIRSTEN%2C+L&rft.inventor=JERECIC%2C+JASNA&rft.date=2005-11-24&rft.externalDBID=A2&rft.externalDocID=WO2005110056A2 |