PREPARATION OF 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES

• Main Authors: VANDERPLAS, BRIAN, CLEMENT, COE, JOTHAM, WADSWORTH, MCHARDY, STANTON, FURST, TICKNER, DEREK, LAWRENCE, RAGAN, JOHN, ANTHONY
• Format: Patent
• Language: English; French
• Published: 28.04.2005
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

This present invention relates to a new and improved reductive amination process for the preparation of 3-azabicyclo[3.1.0]hexane derivatives of formula I comprising reacting a compound of formula II with a compound of formula III. L'invention concerne un nouveau procédé perfectionné d'ami...