NOVEL HUMAN PROTEINS, POLYNUCLEOTIDES ENCODING THEM AND METHODS OF USING THE SAME

• Main Authors: ZERHUSEN, BRYAN, D, EDINGER, SHLOMIT, R, ZHONG, MEI, MALYANKAR, URIEL, M, PENA, CAROL, E., A, BURGESS, CATHERINE, E, ROTHENBERG, MARK, E, GUO, XIAOJIA, PATTURAJAN, MEERA, JI, WEIZHEN, SCIORE, PAUL, CASMAN, STACIE, J, GORMAN, LINDA, PADIGARU, MURALIDHARA, TAUPIER, RAYMOND, J., JR, KEKUDA, RAMESH, MILLER, CHARLES, E, BOLDOG, FERENC, L, STONE, DAVID, J
• Format: Patent
• Language: English; French
• Published: 22.07.2004
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. L'invention concerne des séquences d'acides nucléiques qui codent de nouveaux polypeptides. Elle concerne également des polypeptides codés par ces séquences d'acides nucléiques et des anticorps qui se lient de manière immunospécifique au polypeptide, ainsi que des dérivés, variants, mutants ou fragments du nouveau polypeptide, polynucléotide ou anticorps spécifique au polypeptide. L'invention concerne aussi des vecteurs, cellules hôtes, anticorps et procédés recombinants pour fabriquer ces polypeptides et polynucléotides ainsi que des procédés pour les utiliser. L'invention concerne également des procédés thérapeutiques, diagnostiques et de recherche destinés au diagnostic, au traitement et à la prévention de troubles comprenant un ou plusieurs de ces nouveaux acides nucléiques ou protéines humaines.