FIBROBLAST GROWTH FACTOR AND NUCLEIC ACID ENCODING SAME

• Main Authors: LEPLEY, DENISE, M, LAROCHELLE, WILLIAM, J, ZHONG, MEI, PENA, CAROL, E., A, ALSOBROOK, JOHN, P., II, SHIMKETS, RICHARD, A, BURGESS, CATHERINE, E, HERRMANN, JOHN, L, GROSSE, WILLIAM, M, FERNANDES, ELMA, R, JEFFERS, MICHAEL, E, YANG, MEIJIA, LICHENSTEIN, HENRI, S, GORMAN, LINDA, PRAYAGA, SUDHIRDAS, K, RIEGER, DANIEL, K, PADIGARU, MURALIDHARA, BOLDOG, FERENC, L
• Format: Patent
• Language: English; French
• Published: 28.08.2003
• Edition: 7
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS OR TEST PAPERS THEREFOR; COMPOSITIONS THEREOF; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES; CULTURE MEDIA; ENZYMOLOGY; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROCESSES OF PREPARING SUCH COMPOSITIONS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; TESTING; VINEGAR; WINE

The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses. L'invention concerne un polypeptide isolé, FGF-CX, et un polynucléotide codant le FGF-CX, ainsi que des anticorps à liaison immunospécifique avec le FGF-CX ou un dérivé, variant, mutant ou fragment quelconque de FGF-CX, de polynucléotide ou d'anticorps. L'invention concerne également des procédés relatifs à l'utilisation de FGF-CX, de polynucléotide ou d'anticorps, pour la détection et le traitement d'un large éventail d'états pathologiques, et pour d'autres applications.