CYK-4 POLYPEPTIDES, DNA MOLECULES ENCODING THEM AND THEIR USE IN SCREENING METHODS
Mammalian CYK-4 polypeptides, which are key molecules required for cytokinesis, and DNA molecules encoding them. Screening methods based on biochemical reactions relevant for the function of CYK-4 can be employed to identify compounds interfering with cell division. Such compounds are useful in tumo...
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Main Authors | , , , , |
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Format | Patent |
Language | English French |
Published |
05.12.2002
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | Mammalian CYK-4 polypeptides, which are key molecules required for cytokinesis, and DNA molecules encoding them. Screening methods based on biochemical reactions relevant for the function of CYK-4 can be employed to identify compounds interfering with cell division. Such compounds are useful in tumour therapy.
L'invention concerne des polypeptides CYK-4 étant des molécules clé nécessaires à la cytocinèse, ainsi que des molécules d'ADN codant ces polypeptides. Des procédés de criblage reposant sur des réactions biochimiques nécessaires à l'activité de CYK-4 peuvent être employés afin d'identifier des composés interférant avec la division cellulaire. De tels composés servent au traitement des tumeurs. |
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Bibliography: | Application Number: WO2001EP06797 |