MODIFIED LEUKOTOXIN GENE AND PROTEIN

• Main Authors: STROMMER, JUDITH, N, LEE, RAYMOND, W., H, LO, REGGIE, Y., C, HODGINS, DOUG, SHEWEN, PATRICIA, E
• Format: Patent
• Language: English; French
• Published: 10.01.2002
• Edition: 7
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, preferably from Mannheimia haemolyti...