Reduction of flake-like aggregation in nanoparticulate active agent compositions

• Main Authors: Ryde, Niels P, Liu, Wei, Snyder, Peter, Slifer, David M
• Format: Patent
• Language: English
• Published: 22.05.2018
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

This invention is directed to reduction of flake-like aggregation in nanoparticulate compositions. Also encompassed by the invention are compositions comprising a nanoparticulate active agent, at least one surface stabilizer and a flake-like aggregation reducing agent, such as a buffer and a sugar....