Pharmaceutical composition with improved bioavailability

The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.

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Bibliographic Details
Main Authors Ma Hua, Sandhu Harpreet K, Zhang Yu-E, Lomuscio Steve, Matchett Michael Allen, Shah Navnit Hargovindas
Format Patent
LanguageEnglish
Published 30.08.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The invention relates to solid dispersions of poorly water soluble compounds, in particular Compound A as disclosed herein, formed by solvent co-precipitation or spray drying, resulting in improved bioavailability, safety and tolerability of said compounds.
Bibliography:Application Number: US201414159679