Universal fibronectin type III binding-domain libraries

Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.

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Main Authors CAPPUCCILLI GUIDO, KIRK PETER B, LISTON DAVID R, CREA ROBERTO, SHEN RANDY, HOKANSON CRAIG A
Format Patent
LanguageEnglish
Published 28.06.2016
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Abstract Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
AbstractList Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding affinities, e.g., greater than 300 nM, for VEGFR2 or Axl proteins.
Author SHEN RANDY
LISTON DAVID R
CREA ROBERTO
CAPPUCCILLI GUIDO
HOKANSON CRAIG A
KIRK PETER B
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– fullname: HOKANSON CRAIG A
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RelatedCompanies SHEN RANDY
LISTON DAVID R
CREA ROBERTO
CAPPUCCILLI GUIDO
HOKANSON CRAIG A
KIRK PETER B
PROTELICA, INC
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Snippet Fibronectin Type III (FN3) polypeptide libraries are described, along with their use in identifying fibronectin-type binding peptides having high binding...
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SubjectTerms BEER
BIOCHEMISTRY
CHEMISTRY
COMBINATORIAL CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
Title Universal fibronectin type III binding-domain libraries
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