Recombinant human G-CSF dimer and use thereof for the treatment of neurological diseases
This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural injury in animal, this invention can be used to protect neurons with the use of rhG-CSF dimer such that function of injured nerves can be res...
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| Main Authors | , , , , |
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| Format | Patent |
| Language | English |
| Published |
01.03.2016
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| Subjects | |
| Online Access | Get full text |
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| Abstract | This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural injury in animal, this invention can be used to protect neurons with the use of rhG-CSF dimer such that function of injured nerves can be restored. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased. |
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| AbstractList | This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural injury in animal, this invention can be used to protect neurons with the use of rhG-CSF dimer such that function of injured nerves can be restored. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased. |
| Author | HUANG ZHIHUA HUANG YULIANG YANG HONGZHOU YAN XIAOQIANG SUN BILL N. C |
| Author_xml | – fullname: HUANG YULIANG – fullname: YAN XIAOQIANG – fullname: YANG HONGZHOU – fullname: SUN BILL N. C – fullname: HUANG ZHIHUA |
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| RelatedCompanies | GENERON (SHANGHAI) CORPORATION LTD |
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| Snippet | This invention relates to a recombinant human G-CSF (rhG-CSF) dimer and its use in the treatment of neurological disorder. In particular, upon ischemic neural... |
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| Title | Recombinant human G-CSF dimer and use thereof for the treatment of neurological diseases |
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