Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile

A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.

Saved in:
Bibliographic Details
Main Authors ENGSTROM KENNETH M, MCDERMOTT TODD S, KRUGER ALBERT, BHAGAVATULA LAKSHMI, BORCHARDT THOMAS B, WAGAW SEBLE H, WITTENBERGER STEVEN J, ROZEMA MICHAEL J, GANDARILLA JORGE, FICKES MICHAEL G
Format Patent
LanguageEnglish
Published 16.02.2016
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
Bibliography:Application Number: US20070779936