Process for the preparation of dronedarone by oxidation of a sulphenyl group

• Main Authors: DOMBRÁDY ZSOLT, HEGEDUS ADRIENN, HUSZÁR CSABA
• Format: Patent
• Language: English
• Published: 02.02.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention relates to a novel process for the preparation of dronedarone (I) and pharmaceutically acceptable salts thereof which comprises oxidizing a compound of formula (IV) or a salt thereof with an oxidizing agent in an organic or inorganic solvent or solvent mixture, and isolating the obtain...