Salt form of a multi-arm polymer-drug conjugate
Among other aspects, provided herein is a hydrohalide salt of a multi-arm water-soluble polyethylene glycol-drug conjugate, along with related methods of making and using the same. The hydrohalide salt is stably formed, and appears to be more resistant to hydrolytic degradation than the correspondin...
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Main Authors | , , , , , , , , , , , , |
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Format | Patent |
Language | English |
Published |
05.01.2016
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Subjects | |
Online Access | Get full text |
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Summary: | Among other aspects, provided herein is a hydrohalide salt of a multi-arm water-soluble polyethylene glycol-drug conjugate, along with related methods of making and using the same. The hydrohalide salt is stably formed, and appears to be more resistant to hydrolytic degradation than the corresponding free base form of the conjugate. |
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Bibliography: | Application Number: US201013510587 |