Cross-linkers and their uses

• Main Authors: WIDDISON WAYNE C, KOVTUN YELENA, CHARI RAVI V. J, ZHAO ROBERT YONGXIN, SINGH RAJEEVA
• Format: Patent
• Language: English
• Published: 23.06.2015
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Charged or pro-charged cross-linking moieties and conjugates of cell binding agents and drugs comprising the charged or pro-charged cross-linking moieties and method of making the same.