Antibody having anti-cancer activity

• Main Authors: ATARASHI KAZUYUKI, SHIMIZU EMI, KAJIKAWA MASUNORI, SUGIURA MASAHITO, MATSUMI CHIEMI, SAITOH YUKIE
• Format: Patent
• Language: English
• Published: 09.09.2014
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

By utilizing an SST-REX method, a cDNA encoding a protein expressed on a cell surface or secreted from the cell was selected from a cDNA library derived from a cancer cell line. Monoclonal antibodies against the protein encoding the selected cDNA were prepared. The in vitro and in vivo anti-cancer a...