Dipeptoid prodrugs and the use thereof

The present application relates to dipeptide-like prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)-4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, an...

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Main Authors ALBRECHT-KÜPPER BARBARA, LERCHEN HANS-GEORG, VAKALOPOULOS ALEXANDROS, NELL PETER, MEIBOM DANIEL, ZIMMERMANN KATJA, KRENZ URSULA, KELDENICH JOERG
Format Patent
LanguageEnglish
Published 03.06.2014
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract The present application relates to dipeptide-like prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)-4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
AbstractList The present application relates to dipeptide-like prodrug derivatives of 2-amino-6-({[2-(4-chlorophenyl)-1,3-oxazol-4-yl]methyl}sulfanyl)-4-(4-{[2,3-dihydroxypropyl]oxy}phenyl)pyridine-3,5-dicarbonitrile, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of cardiovascular disorders.
Author LERCHEN HANS-GEORG
MEIBOM DANIEL
ALBRECHT-KÜPPER BARBARA
KRENZ URSULA
VAKALOPOULOS ALEXANDROS
KELDENICH JOERG
ZIMMERMANN KATJA
NELL PETER
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– fullname: KRENZ URSULA
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MEIBOM DANIEL
ALBRECHT-KÜPPER BARBARA
KRENZ URSULA
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KELDENICH JOERG
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NELL PETER
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Dipeptoid prodrugs and the use thereof
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