Engineered nucleic acids encoding a modified erythropoietin and their expression

Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.

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Main Authors ELBASHIR SAYDA M, AFEYAN NOUBAR B, SIECZKIEWICZ GREGORY J, SCHRUM JASON P, BANCEL STEPHANE, DE FOUGEROLLES ANTONIN
Format Patent
LanguageEnglish
Published 29.04.2014
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Abstract Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
AbstractList Provided are formulations, compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the delivery of biological moieties, and are useful for production of proteins.
Author ELBASHIR SAYDA M
DE FOUGEROLLES ANTONIN
SIECZKIEWICZ GREGORY J
AFEYAN NOUBAR B
SCHRUM JASON P
BANCEL STEPHANE
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– fullname: DE FOUGEROLLES ANTONIN
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RelatedCompanies ELBASHIR SAYDA M
DE FOUGEROLLES ANTONIN
MODERNA THERAPEUTICS, INC
SIECZKIEWICZ GREGORY J
AFEYAN NOUBAR B
SCHRUM JASON P
BANCEL STEPHANE
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SubjectTerms CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
Title Engineered nucleic acids encoding a modified erythropoietin and their expression
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