Polymeric artificial tear system
The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
01.04.2014
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations. |
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| AbstractList | The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans such as guar or hydroxypropyl guar and a borate source such as boric acid. The formulations further comprise a cis-diol such as sorbitol that interferes with the cross-linking of galactomannan and borate. Optionally, the formulations are substantially free of divalent cations. |
| Author | DAVIS JAMES W KETELSON HOWARD ALLEN MEADOWS DAVID L |
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| RelatedCompanies | DAVIS JAMES W ALCON RESEARCH, LTD KETELSON HOWARD ALLEN MEADOWS DAVID L |
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| Snippet | The present invention relates to artificial tear formulations and ophthalmic formulations suitable for drug delivery. The formulations comprise galactomannans... |
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| SubjectTerms | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| Title | Polymeric artificial tear system |
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