Triazole derivatives for treatment of Alzheimer's disease

• Main Authors: KATTAR SAM, ZHOU HUA, CHICHETTI STEPHANIE, SCHELL ADAM J, MUNOZ BENITO, METHOT JOEY, BROWN WILLIAM COLBY, AHEARN SEAN P, RIVKIN ALEXEY A, ROSENAU ANDREW, FISCHER CHRISTIAN, CHRISTOPHER MATTHEW, LI CHAOMIN, MACCOSS RACHEL N
• Format: Patent
• Language: English
• Published: 05.11.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

According to the invention there is provided a compound of formula I or a pharmaceutically acceptable salt or hydrate thereof; wherein the variables are as defined herein. The compounds selectively attenuate the production of Abeta42 and hence are useful in treatment of Alzheimer's disease and...