Modeling of the point-spread-function in single-pinhole and multi-pinhole spect reconstruction

• Main Authors: SMITH ANNE M, MINTZER ROBERT A, AUSTIN DEREK W, FENG BING, CHEN MU
• Format: Patent
• Language: English
• Published: 05.03.2013
• Subjects: MEASUREMENT OF NUCLEAR OR X-RADIATION; MEASURING; PHYSICS; TESTING

A system and method for reconstructing single photon emission computed tomography data acquired with a pinhole collimator includes sub-dividing each voxel in the imaging target object space into sub-voxels and sub-dividing each of the detector bins in the gamma camera detector into sub-bins, connecting the centers of each of the sub-voxels to each of the detector sub-bins through a pinhole provided in the pinhole collimator by ray tracing and for each ray connecting the centers of each of the sub-voxels to each of the detector sub-bins, the transmission probability is calculated by analytically solving the intersections between the ray and the pinhole surfaces. Then, a geometric-response-function of the pinhole collimator is computed which is then convolved with the intrinsic-response-function of the detector to obtain the PSF.