Substituted pyridines and pyridazines with angiogenesis inhibiting activity

• Main Authors: SU NING, KLUENDER HAROLD C. E, LEE WENDY, DUMAS JACQUES P, JOE TEDDY K, NAGARATHNAM DHANAPALAN, DIXON JULIE A, SIBLEY ROBERT N, BOYER STEPHEN J
• Format: Patent
• Language: English
• Published: 12.07.2011
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

Substituted and pyridines and pyridazines having angiogenesis inhibiting activity and the generalized structural formula wherein the ring containing A, B, D, E, and L is phenyl or a nitrogen-containing heterocycle; groups X and Y may be any of a variety of defined linking units; R1 and R2 may be def...