Method for the production of oxazoles by condensing aromatic aldehydes with α-ketoximes to N-oxides and then reacting the same with activated acid derivatives

• Main Authors: LAUX WOLFGANG, STUEDEMANN THOMAS, HOLLA WOLFGANG, HOERLEIN ROLF-LUDWIG, TAPPERTZHOFEN CHRISTOPH, SCHEFFER ROBERT J. H, KULITZSCHER BERNDT
• Format: Patent
• Language: English
• Published: 02.11.2010
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention is related to a process for preparing compounds of the formula IV by means of conversion of aromatic aldehydes of the formula I using α-ketoximes of the formula II via N-oxides of the formula III to halomethyloxazoles of the formula IV, wherein R1, R2, R3, R4, R5, R6, R7, R8, X1, X2, X...