Rapid classification of biological components
A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamin...
Saved in:
Main Authors | , , |
---|---|
Format | Patent |
Language | English |
Published |
23.03.2010
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity. |
---|---|
AbstractList | A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In an illustrative embodiment of the invention, the analyte is a drug, such as marijuana, Cocaine (crystalline tropane alkaloid), methamphetamine, methyltestosterone, or mesterolone. The method involves attaching antigens of the surface of a solid support in a preselected pattern to form an array wherein the locations of the antigens are known; contacting the array with the biological sample such that a portion of antibodies in the sample reacts with and binds to antigens in the array, thereby forming immune complexes; washing away antibodies that do not form immune complexes; and detecting the immune complexes, thereby forming an antibody profile. Forensic samples are identified by comparing a sample from an unknown source with a sample from a known source. Further, an assay, such as a test for illegal drug use, can be coupled to a test for identity such that the results of the assay can be positively correlated to a subject's identity. |
Author | BARRETT KAREN B THOMPSON VICKI S KEY DIANE E |
Author_xml | – fullname: KEY DIANE E – fullname: THOMPSON VICKI S – fullname: BARRETT KAREN B |
BookMark | eNrjYmDJy89L5WTQDUosyExRSM5JLC7OTMtMTizJzM9TyE9TSMrMz8lPBwrkKCTn5xYAFeeVFPMwsKYl5hSn8kJpbgYFN9cQZw_d1IL8-NTigsTk1LzUkvjQYHMzCyNzSwsnI2MilAAAjOosLg |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences Physics |
ExternalDocumentID | US7682798B2 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_US7682798B23 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 12:25:13 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_US7682798B23 |
Notes | Application Number: US20050101254 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100323&DB=EPODOC&CC=US&NR=7682798B2 |
ParticipantIDs | epo_espacenet_US7682798B2 |
PublicationCentury | 2000 |
PublicationDate | 20100323 |
PublicationDateYYYYMMDD | 2010-03-23 |
PublicationDate_xml | – month: 03 year: 2010 text: 20100323 day: 23 |
PublicationDecade | 2010 |
PublicationYear | 2010 |
RelatedCompanies | BATTELLE ENERGY ALLIANCE, LLC |
RelatedCompanies_xml | – name: BATTELLE ENERGY ALLIANCE, LLC |
Score | 2.7705252 |
Snippet | A method is disclosed for analyzing a biological sample by antibody profiling for identifying forensic samples or for detecting the presence of an analyte. In... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TECHNICAL SUBJECTS COVERED BY FORMER USPC TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ARTCOLLECTIONS [XRACs] AND DIGESTS TESTING |
Title | Rapid classification of biological components |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100323&DB=EPODOC&locale=&CC=US&NR=7682798B2 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV07T8MwED5V5blBAFFeyoCyWTRxS-IhQspLFRJt1TaoW1W7jpQliUgQf5-zmxYWWG3LOp995_P582eAR8pxluU6Ixh8CJWtYoQ7ghPBNn07c11BhUb5jp9H6eB1OVx2IN-9hdE8oV-aHBEtSqC9N9pfVz9JrEhjK-snnmNR-ZIs_MhqT8c2rlGHWlHgx9NJNAmtMPTTuTWe-RhVOy7zAvTWByqKVjT78XugHqVUv3eU5AwOp9hZ0ZxDRxYGnIS7j9cMOH5r77sNONIATVFjYWuE9QWQ2brKN6ZQca8C-mhxzTIzt4RKSuumQoqXhQJJXIKZxItwRFCC1X60q3S-l5VeQbfAxtdg2oxJezBkG8X2wjjzMtGXnsull6FTk7QHvT-7ufmn7hZOt_fhlDj0DrrNx6e8x2224Q9aQd_KqIH_ |
link.rule.ids | 230,309,786,891,25594,76903 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3NT8IwFH8h-IE3RQ342YPZbZGt4NbDYsLGgspXYDPcCC1dwmUsbsZ_39cy0IteX5vm9eN99f36CvBAOe6yXCYmOh9C3VYxk9uCm4KtWlbiOIIKjfIdPfXj9uu8M6_AevcWRtcJ_dLFEVGiBMp7ofV19nOJFWhsZf7I10jaPIeRFxhldGzhGbWpEXS93mQcjH3D9714ZoymHnrVtsPcLmrrAwcjQh0pvXfVo5Tst0UJT-FwgoOlxRlUZFqHmr_7eK0Ox8My312HIw3QFDkSSyHMz8GcLrP1igjl9yqgj2aXbBKyLaikVp0opPgmVSCJCyBhL_L7JnKw2M92Ec_2vNJLqKbYuQHEYkxa7Q5bqWovjDM3ES3pOly6CSo1SZvQ_HOYq3_a7qHWj4aDxeBl9HYNJ9vcODVtegPV4uNT3qLJLfidXqxvBB2E6Q |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Rapid+classification+of+biological+components&rft.inventor=KEY+DIANE+E&rft.inventor=THOMPSON+VICKI+S&rft.inventor=BARRETT+KAREN+B&rft.date=2010-03-23&rft.externalDBID=B2&rft.externalDocID=US7682798B2 |