Method of producing an antiangiogenic or vascular permeability reducing effect

• Main Authors: POYSER JEFFREY PHILIP, MCKERRECHER DARREN, PLE PATRICK, LAMBERT CHRISTINE MARIE PAUL, HENNEQUIN LAURENT FRANCOIS ANDRE, CRAWLEY GRAHAM CHARLES
• Format: Patent
• Language: English
• Published: 03.03.2009
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention concerns the use of a quinazoline derivative of Formula (I) wherein Q1 includes a quinazoline ring optionally substituted with a group such as halogeno, trifluoromethyl and cyano, or a group of the formula: Q3-X1- wherein X1 includes a direct bond and O and Q3includes aryl, aryl-(1-6C)...