8-Quinolinxanthine and 8-isoquinolinxanthine derivatives as PDE 5 inhibitors

• Main Authors: NAEF RET, GOMEZ SYLVIE FELICITE, SANDHAM DAVID ANDREW, FAIRHURST ROBIN ALEC, BHALAY GURDIP, COLLINGWOOD STEPHEN PAUL
• Format: Patent
• Language: English
• Published: 19.07.2005
• Edition: 7
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

A compound of formula (I) R1 is hydrogen or alkyl optionally substituted by hydroxy, alkoxy, or alkylthio, R2 is hydrogen, alkyl, hydroxyalkyl, alkylcarbonyloxyalkyl, alkoxyalkyl, alkylthioalkyl, alkenyl, cycloalkylalkyl, heterocyclylalkyl, aralkyl in which the aryl ring thereof is optionally fused...