Crude extract from Viscum album coloratum, and proteins and lectins isolated therefrom

• Main Authors: SONG SEONGKYU, SUH BYUNGSUN, KIM JONGBAE, KWAK JINHWAN, YOON TAEKJOON, KANG TAEBONG, LEE KWANHEE, PARK CHOONHO, DOO MYOUNGSOOL, SONG BYEOUNGDOO
• Format: Patent
• Language: English
• Published: 25.01.2005
• Edition: 7
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Disclosed is an extract from Korean mistletoe KM-110, which is of immunity enhancement and activity against tumor metastasis and can be used as an adjuvant material for vaccines applicable for the induction of humoral and cell-mediated immunity. Also disclosed are its fractions, a protein fraction KM-AS, a lectin fraction KML-C, lectin components KML-IIU and KML-IIL, which both are further purified from lectin fraction KML-C, a protein KMHBP which is obtained through heparin binding chromatography eluting with NaCl from a fraction C-free AS which is a portion of the KM-AS free of KML-C, and a mixture KM of the KMHBP and the KML-C. They are revealed as to their roles in the humoral and cell-mediated immunity enhancement and antitumoral activity.