Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof

Provided herein are compounds of the formula (I):wherein R1-R8 are as described herein, R4 being aryl or heteroaryl Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine or dopamine.

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Bibliographic Details
Main Authors CURRY MATT A, BECK JAMES P, SMITH MARK A
Format Patent
LanguageEnglish
Published 17.06.2003
Edition7
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Abstract Provided herein are compounds of the formula (I):wherein R1-R8 are as described herein, R4 being aryl or heteroaryl Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine or dopamine.
AbstractList Provided herein are compounds of the formula (I):wherein R1-R8 are as described herein, R4 being aryl or heteroaryl Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreased availability of serotonin, norepinephrine or dopamine.
Author CURRY MATT A
SMITH MARK A
BECK JAMES P
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Snippet Provided herein are compounds of the formula (I):wherein R1-R8 are as described herein, R4 being aryl or heteroaryl Such compounds are particularly useful in...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Aryl and heteroaryl substituted tetrahydroisoquinolines and use thereof
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