Preparation of 2-keto-L-gulonic esters

• Main Authors: BOETTCHER ANDREAS, BURST WOLFRAM
• Format: Patent
• Language: English
• Published: 03.06.2003
• Edition: 7
• Subjects: APPARATUS THEREFOR; CHEMISTRY; DERIVATIVES THEREOF; GENERAL METHODS OF ORGANIC CHEMISTRY; METALLURGY; NUCLEIC ACIDS; NUCLEOSIDES; NUCLEOTIDES; ORGANIC CHEMISTRY; SUGARS

C1-C10-alkyl 2-keto-L-gulonates are prepared by esterifying 2-keto-L-gulonic acid or diacetone-2-keto-L-gulonic acid with a C1-C10-alcohol in the presence of an acidic catalyst by a process in which the esterification is carried out in a liquid film on a hot surface with simultaneous removal of wate...