C5-specific antibodies for the treatment of inflammatory diseases
The use of anti-C5 antibodies, e.g., monoclonal antibodies, to treat glomerulonephritis (GN) is disclosed. The administration of such antibodies at low dosage levels has been found to significantly reduce glomerular inflammation/enlargement and other pathologic conditions associated with GN. Also di...
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Main Authors | , , , , , , , , , |
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Format | Patent |
Language | English |
Published |
12.03.2002
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Edition | 7 |
Subjects | |
Online Access | Get full text |
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Summary: | The use of anti-C5 antibodies, e.g., monoclonal antibodies, to treat glomerulonephritis (GN) is disclosed. The administration of such antibodies at low dosage levels has been found to significantly reduce glomerular inflammation/enlargement and other pathologic conditions associated with GN. Also disclosed are anti-C5 antibodies and anti-C5 antibody-encoding nucleic acid molecules. These antibodies are useful in the treatment of GN and other inflammatory conditions involving pathologic activation of the complement system. |
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Bibliography: | Application Number: US19950487283 |