Human pluripotent hematopoietic colony stimulating factor
Highly purified Pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells has been highly purified from low serum-containing conditioned medium to apparant homogeneity. Pluripotent CSF supports the growth of human m...
Saved in:
Main Authors | , , , , |
---|---|
Format | Patent |
Language | English |
Published |
02.07.1996
|
Edition | 6 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Highly purified Pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells has been highly purified from low serum-containing conditioned medium to apparant homogeneity. Pluripotent CSF supports the growth of human mixed colonies (CFU-GEMM), granulocyte-macrophage colonies (CFU-GM), early erythroid colonies (BFU-E) and induces differentiation of human leukemic cells. The specific activity of the purified pluripotent CSF in the CFU-GM assay is 1.5x108 U/mg protein. |
---|---|
AbstractList | Highly purified Pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells has been highly purified from low serum-containing conditioned medium to apparant homogeneity. Pluripotent CSF supports the growth of human mixed colonies (CFU-GEMM), granulocyte-macrophage colonies (CFU-GM), early erythroid colonies (BFU-E) and induces differentiation of human leukemic cells. The specific activity of the purified pluripotent CSF in the CFU-GM assay is 1.5x108 U/mg protein. |
Author | PLATZER; ERICH GABRILOVE; JANICE L MERTELSMANN; ROLAND WELTE; KARL MOORE; MALCOLM A. S |
Author_xml | – fullname: WELTE; KARL – fullname: PLATZER; ERICH – fullname: MOORE; MALCOLM A. S – fullname: GABRILOVE; JANICE L – fullname: MERTELSMANN; ROLAND |
BookMark | eNqFyq0OAjEMAOAJEPw9A30BBIwTSEIg5wF9aZYeNNna5tYJ3h6DR33mW4aZqNAinPpWUMBym9jUSRzeVNDVlMk5QdKs8oHqXFpGZ3nBiMl1Wof5iLnS5ucqbG_Xx6XfkelA1TCRkA_Pe9fFQzzuz_H_-AIDlzDE |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
Edition | 6 |
ExternalDocumentID | US5532341A |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_US5532341A3 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 15:20:12 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_US5532341A3 |
Notes | Application Number: US19940280582 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960702&DB=EPODOC&CC=US&NR=5532341A |
ParticipantIDs | epo_espacenet_US5532341A |
PublicationCentury | 1900 |
PublicationDate | 19960702 |
PublicationDateYYYYMMDD | 1996-07-02 |
PublicationDate_xml | – month: 07 year: 1996 text: 19960702 day: 02 |
PublicationDecade | 1990 |
PublicationYear | 1996 |
RelatedCompanies | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
RelatedCompanies_xml | – name: SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH |
Score | 2.4629781 |
Snippet | Highly purified Pluripotent hematopoietic colony-stimulating factor (pluripotent CSF), a glycoprotein (MW 19,600) constitutively produced by human tumor cells... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE |
Title | Human pluripotent hematopoietic colony stimulating factor |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960702&DB=EPODOC&locale=&CC=US&NR=5532341A |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV1bS8MwFD7MKeqbTmXe-yB9C2Zt08tDEdcLQ9gFt8reRtulOtC2uA7x33uSrerL3kJCDknId3JI8n0H4C7GIINxhxEtNRMidgiJrbRDLGqnDs1iW48FUbg_MHuR8TRl0wa81VwYqRP6JcUREVEp4r2S_rr8u8Ty5d_K5X2ywKriIZy4vjrf0MVM3MGa6nfdYDT0h57qeW40VgfPLmO6hg77cQd2RRAtVPaDl67gpJT_D5TwCPZGaCuvjqHB8xYceHXetRbs9zfP3VjcIG95Ao68bVfK9xWivBBdFSm3WpTFQvAQFaE-nX8riNgPmZErf1XWuXRO4TYMJl6P4Bhmv9OdReN6sPoZNPMi521QWCfDQIXTjNqxMY8xijBMrptMs5KEco2eQ3ublYvtTZdwuP6FbBGqXUGz-lzxazxkq-RGrs8PTjyCnw |
link.rule.ids | 230,309,786,891,25594,76904 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3PT4MwFH6Z0zhvOjXz5zgYbsQOKIwDMQ5YUPcrbpjdFmCdLlEgjsX43_vagXrZrWnTpm36ta_t-74HcBOikUGZRRU1NiKFrxAlNOOWYpJ2bJFF2NZCThTuDww_0B-ndFqBt5ILI3RCv4Q4IiIqRrznYr_O_h6xXOFbubqNlpiV3nUntivPC7qYgStYld2O7Y2G7tCRHccOxvLg2aZUU3HDvt-BXRMvhFxl33vpcE5K9v9A6R7C3gjbSvIjqLCkDjWnjLtWh_1-8d2NyQJ5q2OwxGu7lL2vEeUpryoJudU0S5echyhx9enkW0LEfoiIXMmrtImlcwLNrjdxfAX7MPsd7iwYl53VTqGapAlrgERbCzRUGFmQdqjPQ7QidINpBlXNKCJMJWfQ2NbK-faiJtT8Sb836z0Mni7gYOORbCpEvYRq_rlmV3jg5tG1mKsfj0GFig |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Human+pluripotent+hematopoietic+colony+stimulating+factor&rft.inventor=WELTE%3B+KARL&rft.inventor=PLATZER%3B+ERICH&rft.inventor=MOORE%3B+MALCOLM+A.+S&rft.inventor=GABRILOVE%3B+JANICE+L&rft.inventor=MERTELSMANN%3B+ROLAND&rft.date=1996-07-02&rft.externalDBID=A&rft.externalDocID=US5532341A |