Method of making chlorambucil
Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a hydrogenation catalyst, a 4-p(lower acylamido)-phenyl-5-oxo-butyric acid or a 4-p-(lower acylamido)phenyl-4-oxobut-2-enoic acid. Examples ar...
Saved in:
| Main Authors | , |
|---|---|
| Format | Patent |
| Language | English |
| Published |
24.07.1962
|
| Online Access | Get full text |
Cover
Loading…
| Abstract | Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a hydrogenation catalyst, a 4-p(lower acylamido)-phenyl-5-oxo-butyric acid or a 4-p-(lower acylamido)phenyl-4-oxobut-2-enoic acid. Examples are given. 4-p-(Acetamidophenyl) -4- oxo - but -2- enoic acid is prepared from acetanilide and maleic acid. |
|---|---|
| AbstractList | Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a hydrogenation catalyst, a 4-p(lower acylamido)-phenyl-5-oxo-butyric acid or a 4-p-(lower acylamido)phenyl-4-oxobut-2-enoic acid. Examples are given. 4-p-(Acetamidophenyl) -4- oxo - but -2- enoic acid is prepared from acetanilide and maleic acid. |
| Author | MENTHA JOHN W PHILLIPS ARTHUR P |
| Author_xml | – fullname: MENTHA JOHN W – fullname: PHILLIPS ARTHUR P |
| BookMark | eNrjYmDJy89L5WSQ9U0tychPUchPU8hNzM7MS1dIzsjJL0rMTSpNzszhYWBNS8wpTuWF0twM8m6uIc4euqkF-fGpxQWJyal5qSXxocHGBiZmxgaGjsaEVQAAB8klEA |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | US3046301A |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_US3046301A3 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 13:18:26 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_US3046301A3 |
| Notes | Application Number: US19590849438 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19620724&DB=EPODOC&CC=US&NR=3046301A |
| ParticipantIDs | epo_espacenet_US3046301A |
| PublicationCentury | 1900 |
| PublicationDate | 19620724 |
| PublicationDateYYYYMMDD | 1962-07-24 |
| PublicationDate_xml | – month: 07 year: 1962 text: 19620724 day: 24 |
| PublicationDecade | 1960 |
| PublicationYear | 1962 |
| RelatedCompanies | BURROUGHS WELLCOME & CO. (U.S.A.) INC |
| RelatedCompanies_xml | – name: BURROUGHS WELLCOME & CO. (U.S.A.) INC |
| Score | 2.3233125 |
| Snippet | Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a... |
| SourceID | epo |
| SourceType | Open Access Repository |
| Title | Method of making chlorambucil |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19620724&DB=EPODOC&locale=&CC=US&NR=3046301A |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMUs0Bra6TVJ1kwwNjXWBpZ-ZbpJFmoGuiVGSRapFWrKBEXiHnK-fmUeoiVeEaQQTQwZsLwz4nNBy8OGIwByVDMzvJeDyugAxiOUCXltZrJ-UCRTKt3cLsXVRS4FsFzMzMjA3MlFzcbJ1DfB38XdWc3a2DQ1W8wuyBZ-MZWDoyMzACmpEg07Zdw1zAu1JKUCuUNwEGdgCgGbllQgxMKXmCTNwOsPuXRNm4PCFTncDmdCcVyzCIOsLvupZIT9NIRd8gZRCcgawq52Ym1SanJkjyiDv5hri7KELtCce7qX40GCYg4zFGFiAHf1UCQYFQ7M0gxRjQ-M0k0RLkxQDw0RLIzNzyzRgDgM2ixJTDSQZJHCZIoVbSpqBCxQwoPFIIxMZBpaSotJUWWBFWpIkBw4DAEH_dl0 |
| link.rule.ids | 230,309,786,891,25594,76903 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV1LT4NAEJ7Uaqw3rZr6qOVguBEX2EI5EGOhBLXQxoLpjbA80ib2EUvj33dYi3rpbbObzO5O8s1rd2YA7rVYRaubZhKTZVVC6adJrJcTiSqsl_XyhCg8Q87zNTekL9PutAazKheG1wn94sUREVEJ4r3g8nr9F8Sy-d_KzQOb49Tq0QlMW0x_0sU0hegKFe2-ORiP7JElWpYZTkT_zeSVsYj8dACHOjqE3FF675c5Kev_CsU5haMx0loWZ1DLlk1oWFXftSYce7vnbhzukLc5h7bHWz0Lq1xY8AZSQjJDVztesG0y_7iAjjMILFfCfaLfK0XhpDqQegl1dPSzFgiylpNUldWcxgZNiRwbiqYbOSIMzaI4I1fQ2kflev9SBxpu4A2j4bP_egMnJZPK2KRCb6FefG6zNirVgt1xfnwD7s55Rw |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Method+of+making+chlorambucil&rft.inventor=MENTHA+JOHN+W&rft.inventor=PHILLIPS+ARTHUR+P&rft.date=1962-07-24&rft.externalDBID=A&rft.externalDocID=US3046301A |