Method of making chlorambucil

Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a hydrogenation catalyst, a 4-p(lower acylamido)-phenyl-5-oxo-butyric acid or a 4-p-(lower acylamido)phenyl-4-oxobut-2-enoic acid. Examples ar...

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Main Authors MENTHA JOHN W, PHILLIPS ARTHUR P
Format Patent
LanguageEnglish
Published 24.07.1962
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Abstract Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a hydrogenation catalyst, a 4-p(lower acylamido)-phenyl-5-oxo-butyric acid or a 4-p-(lower acylamido)phenyl-4-oxobut-2-enoic acid. Examples are given. 4-p-(Acetamidophenyl) -4- oxo - but -2- enoic acid is prepared from acetanilide and maleic acid.
AbstractList Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a hydrogenation catalyst, a 4-p(lower acylamido)-phenyl-5-oxo-butyric acid or a 4-p-(lower acylamido)phenyl-4-oxobut-2-enoic acid. Examples are given. 4-p-(Acetamidophenyl) -4- oxo - but -2- enoic acid is prepared from acetanilide and maleic acid.
Author MENTHA JOHN W
PHILLIPS ARTHUR P
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Snippet Methyl 4-p-aminophenylbutyrate is prepared by hydrogenating, in a methanolic solution containing a substantial amount of a strong acid and in the presence of a...
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Title Method of making chlorambucil
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