MIRDAMETINIB TREATMENT
The present disclosure relates to a method for treating certain types of tumors or cancers, such as plexiform neurofibromas (PN), plexiform neurofibromas associated with neurofibromatosis type 1 (NF1-PN), by orally administering an effective amount of mirdametinib to the patient, where an amount of...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
19.09.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | The present disclosure relates to a method for treating certain types of tumors or cancers, such as plexiform neurofibromas (PN), plexiform neurofibromas associated with neurofibromatosis type 1 (NF1-PN), by orally administering an effective amount of mirdametinib to the patient, where an amount of mirdametinib is administered on the first day of treatment to provide (i) an AUCO-tau less than 400 ng·h/mL, (ii) a Cmax no more than 40 ng/mL, or (iii) both. |
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| AbstractList | The present disclosure relates to a method for treating certain types of tumors or cancers, such as plexiform neurofibromas (PN), plexiform neurofibromas associated with neurofibromatosis type 1 (NF1-PN), by orally administering an effective amount of mirdametinib to the patient, where an amount of mirdametinib is administered on the first day of treatment to provide (i) an AUCO-tau less than 400 ng·h/mL, (ii) a Cmax no more than 40 ng/mL, or (iii) both. |
| Author | SHEARER, Todd Webster LANGSETH, Abraham J ILOEJE, Uchenna H |
| Author_xml | – fullname: LANGSETH, Abraham J – fullname: ILOEJE, Uchenna H – fullname: SHEARER, Todd Webster |
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| Notes | Application Number: US202418674104 |
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| RelatedCompanies | SpringWorks Therapeutics, Inc |
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| Snippet | The present disclosure relates to a method for treating certain types of tumors or cancers, such as plexiform neurofibromas (PN), plexiform neurofibromas... |
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| Title | MIRDAMETINIB TREATMENT |
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