SALT AND CRYSTAL FORMS OF AN HMOX1 INDUCER
Disclosed is the 1:1 phosphate salt of Compound (I) as well as a novel crystal form thereof. Also disclosed is a novel crystal form of Compound (I). The present invention also provides methods of increasing the activity of HMOX-1 in a subject, of activating transcription factor Nrf2 in a subject or...
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| Main Authors | , , |
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| Format | Patent |
| Language | English |
| Published |
12.09.2024
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| Subjects | |
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| Abstract | Disclosed is the 1:1 phosphate salt of Compound (I) as well as a novel crystal form thereof. Also disclosed is a novel crystal form of Compound (I). The present invention also provides methods of increasing the activity of HMOX-1 in a subject, of activating transcription factor Nrf2 in a subject or of reducing the amount of ROS in a subject by administering an effective amount of the 1:1 phosphate salt of Compound (I), the crystal form thereof or the crystal form of Compound (I) to the subject. |
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| AbstractList | Disclosed is the 1:1 phosphate salt of Compound (I) as well as a novel crystal form thereof. Also disclosed is a novel crystal form of Compound (I). The present invention also provides methods of increasing the activity of HMOX-1 in a subject, of activating transcription factor Nrf2 in a subject or of reducing the amount of ROS in a subject by administering an effective amount of the 1:1 phosphate salt of Compound (I), the crystal form thereof or the crystal form of Compound (I) to the subject. |
| Author | Hu, Juan Biddle, Margaret Kuang, Shanming |
| Author_xml | – fullname: Kuang, Shanming – fullname: Biddle, Margaret – fullname: Hu, Juan |
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| Notes | Application Number: US202218277746 |
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| Snippet | Disclosed is the 1:1 phosphate salt of Compound (I) as well as a novel crystal form thereof. Also disclosed is a novel crystal form of Compound (I). The... |
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| Title | SALT AND CRYSTAL FORMS OF AN HMOX1 INDUCER |
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