cGAS INHIBITORS

The present invention relates to novel cGAS inhibitor compounds, having a formula of:to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to treat certain pathological conditions such as immune-mediated diseases.

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Main Authors AHMED, Adel, GERNERT, Douglas L, CARSON, Cheryl Ann, TROMICZAK, Eric George, LUGAR, Charles W, FORTNER, Kevin Charles, ONOBUN, Emmanuel, CUMMING, Graham Robert, AGEJAS CHICHARRO, Francisco Javier, NAGARAJAN, Shanthi, MARTINEZ BROKAW, Christina, VARIN, Thibault Francois, GREEN, Steven J, CONNER, Scott Eugene, MARIMUTHU, Jothirajah
Format Patent
LanguageEnglish
Published 25.07.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract The present invention relates to novel cGAS inhibitor compounds, having a formula of:to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to treat certain pathological conditions such as immune-mediated diseases.
AbstractList The present invention relates to novel cGAS inhibitor compounds, having a formula of:to pharmaceutical compositions comprising the compounds, and to methods of using the compounds and compositions to treat certain pathological conditions such as immune-mediated diseases.
Author LUGAR, Charles W
MARTINEZ BROKAW, Christina
AGEJAS CHICHARRO, Francisco Javier
GERNERT, Douglas L
VARIN, Thibault Francois
NAGARAJAN, Shanthi
MARIMUTHU, Jothirajah
CUMMING, Graham Robert
GREEN, Steven J
TROMICZAK, Eric George
ONOBUN, Emmanuel
CONNER, Scott Eugene
FORTNER, Kevin Charles
AHMED, Adel
CARSON, Cheryl Ann
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– fullname: CARSON, Cheryl Ann
– fullname: TROMICZAK, Eric George
– fullname: LUGAR, Charles W
– fullname: FORTNER, Kevin Charles
– fullname: ONOBUN, Emmanuel
– fullname: CUMMING, Graham Robert
– fullname: AGEJAS CHICHARRO, Francisco Javier
– fullname: NAGARAJAN, Shanthi
– fullname: MARTINEZ BROKAW, Christina
– fullname: VARIN, Thibault Francois
– fullname: GREEN, Steven J
– fullname: CONNER, Scott Eugene
– fullname: MARIMUTHU, Jothirajah
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Snippet The present invention relates to novel cGAS inhibitor compounds, having a formula of:to pharmaceutical compositions comprising the compounds, and to methods of...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title cGAS INHIBITORS
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