PRODRUGS OF L-BHDU AND METHODS OF TREATING VIRAL INFECTIONS

• Main Authors: Chu, Chung, Singh, Uma Sharan
• Format: Patent
• Language: English
• Published: 20.06.2024
• Subjects: ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

In an embodiment, the invention is directed to prodrug compounds of L-BHDU according to the chemical structure I:Where R1 is a -(CH2)n-O-R1a group or a -(CH2)j-O-C(O)Ok-R2a group;R2 is H, a -(CH2)n-O-R1a group or a -(CH2)j-O-C(O)Ok- R2a group;R1a is independently a C6-C30alkyl group, often a C12-C22...