MAP4K4 INHIBITORS

This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There ar...

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Main Authors JARVIS, Ashley, MARTIN, Nicholas, PERRIOR, Trevor, LOW, Caroline, NEWTON, Gary, REISINGER, Tifelle, NEGOITA-GIRAS, Gabriel, BAYFORD, Melanie, FISHER, Martin, CHAPMAN, Nicholas, AQIL, Rehan, FIEDLER, Lorna R, CHAPMAN, Katie, SCHNEIDER, Michael
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LanguageEnglish
Published 20.06.2024
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Abstract This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There are also provided processes for producing compounds of the present invention and method of their use. In particular, the present invention relates to compounds of formula (I).
AbstractList This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4 (MAP4K4). The invention also relates to the use of these pyrrolopyrimidine comprising compounds, for example in a method of treatment. There are also provided processes for producing compounds of the present invention and method of their use. In particular, the present invention relates to compounds of formula (I).
Author NEWTON, Gary
BAYFORD, Melanie
FISHER, Martin
SCHNEIDER, Michael
CHAPMAN, Katie
NEGOITA-GIRAS, Gabriel
JARVIS, Ashley
REISINGER, Tifelle
CHAPMAN, Nicholas
AQIL, Rehan
PERRIOR, Trevor
LOW, Caroline
MARTIN, Nicholas
FIEDLER, Lorna R
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– fullname: LOW, Caroline
– fullname: NEWTON, Gary
– fullname: REISINGER, Tifelle
– fullname: NEGOITA-GIRAS, Gabriel
– fullname: BAYFORD, Melanie
– fullname: FISHER, Martin
– fullname: CHAPMAN, Nicholas
– fullname: AQIL, Rehan
– fullname: FIEDLER, Lorna R
– fullname: CHAPMAN, Katie
– fullname: SCHNEIDER, Michael
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Snippet This invention relates to pyrrolopyrimidine comprising compounds that may be useful as inhibitors of Mitogen-activated Protein Kinase Kinase Kinase Kinase-4...
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SubjectTerms ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title MAP4K4 INHIBITORS
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