Chemically Coupled Transporter for Low-Hydrophobicity Bioactive Drugs into the Central Nervous System

The present disclosure provides a compound comprising a modified tetracycline derivative, covalently coupled through a linker defined by the generic formula XZX to a low-hydrophobicity bioactive molecule useful for treating neurodegenerative diseases, particularly a compound wherein the modified tet...

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Main Authors Luong, Martin, Chaves, Analía Silvina, Varela, Oscar José, Socías, Sergio Benjamin, Kolender, Adriana Andrea, Pingitore, Esteban Vera, Pernicone, Agustín Osvaldo, Tomas Grau, Rodrigo Hernán, González Lizárraga, Maria Florencia, Chehín, Rosana Nieves, Ávila, Cesar Luis, Ploper, Diego, Manzano, Verónica Elena
Format Patent
LanguageEnglish
Published 20.06.2024
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