2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS

Provided herein are compounds according to Formula (I)or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonis...

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Main Authors CALHOUN, Amy, GARDINIER, Kevin Matthew, THOMSON, Christopher G, PALACIOS, Daniel Steven, QIAN, Ming, YANG, Fan, JENDZA, Keith, NEEF, James Anthony, WANG, Kate Yaping, CHEN, Xin, LABBE-GIGUERE, Nancy, HALL, Edward Charles, SHULTZ, Michael David
Format Patent
LanguageEnglish
Published 02.05.2024
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Provided herein are compounds according to Formula (I)or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.
AbstractList Provided herein are compounds according to Formula (I)or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) as well as the use of such compounds as M4 receptor agonists.
Author QIAN, Ming
WANG, Kate Yaping
LABBE-GIGUERE, Nancy
GARDINIER, Kevin Matthew
CALHOUN, Amy
NEEF, James Anthony
THOMSON, Christopher G
CHEN, Xin
HALL, Edward Charles
JENDZA, Keith
SHULTZ, Michael David
YANG, Fan
PALACIOS, Daniel Steven
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– fullname: GARDINIER, Kevin Matthew
– fullname: THOMSON, Christopher G
– fullname: PALACIOS, Daniel Steven
– fullname: QIAN, Ming
– fullname: YANG, Fan
– fullname: JENDZA, Keith
– fullname: NEEF, James Anthony
– fullname: WANG, Kate Yaping
– fullname: CHEN, Xin
– fullname: LABBE-GIGUERE, Nancy
– fullname: HALL, Edward Charles
– fullname: SHULTZ, Michael David
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Snippet Provided herein are compounds according to Formula (I)or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R5, and R7 are defined herein. Also...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 2-AZASPIRO[3.4]OCTANE DERIVATIVES AS M4 AGONISTS
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