SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS
The invention relates to substituted pyrazolo piperidine carboxylic acids, their salts and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular and cardiac diseases, preferably heart failure...
Saved in:
Main Authors | , , , , , , , , , , , , , |
---|---|
Format | Patent |
Language | English |
Published |
28.03.2024
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The invention relates to substituted pyrazolo piperidine carboxylic acids, their salts and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular and cardiac diseases, preferably heart failure with reduced and preserved ejection fraction (HFrEF, HFmrEF and HFpEF), hypertension (HTN), peripheral arterial diseases (PAD, PAOD), cardio-renal and kidney diseases, preferably chronic and diabetic kidney disease (CKD and DKD), cardiopulmonary and lung diseases, preferable pulmonary hypertension (PH), and other diseases, preferably neurodegenerative diseases and different forms of dementias, fibrotic diseases, systemic sclerosis (SSc), sickle cell disease (SCD), wound healing disorders such as diabetic foot ulcer (DFU). |
---|---|
AbstractList | The invention relates to substituted pyrazolo piperidine carboxylic acids, their salts and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular cardiovascular and cardiac diseases, preferably heart failure with reduced and preserved ejection fraction (HFrEF, HFmrEF and HFpEF), hypertension (HTN), peripheral arterial diseases (PAD, PAOD), cardio-renal and kidney diseases, preferably chronic and diabetic kidney disease (CKD and DKD), cardiopulmonary and lung diseases, preferable pulmonary hypertension (PH), and other diseases, preferably neurodegenerative diseases and different forms of dementias, fibrotic diseases, systemic sclerosis (SSc), sickle cell disease (SCD), wound healing disorders such as diabetic foot ulcer (DFU). |
Author | DIESKAU, Andre STELLFELD, Timo SANDNER, Peter VAKALOPOULOS, Alexandros BOULTADAKIS-ARAPINIS, Melissa HOFMEISTER, Lucas Hudson COLLIN-KRÖPELIN, Marie-Pierre CANDISH, Lisa DIETZ, Lisa MATHAR, Ilka SCHMECK, Carsten WEBSTER, Robert Alan ORTEGA HERNANDEZ, Nuria WUNDER, Frank |
Author_xml | – fullname: SANDNER, Peter – fullname: WEBSTER, Robert Alan – fullname: STELLFELD, Timo – fullname: BOULTADAKIS-ARAPINIS, Melissa – fullname: MATHAR, Ilka – fullname: COLLIN-KRÖPELIN, Marie-Pierre – fullname: HOFMEISTER, Lucas Hudson – fullname: DIETZ, Lisa – fullname: SCHMECK, Carsten – fullname: WUNDER, Frank – fullname: DIESKAU, Andre – fullname: CANDISH, Lisa – fullname: VAKALOPOULOS, Alexandros – fullname: ORTEGA HERNANDEZ, Nuria |
BookMark | eNrjYmDJy89L5WQwCA51Cg7xDAkNcXVRCIgMcozy9_FXCPAMcA3ydPH0c1Vwdgxy8o-I9PF0VnB09nQJ5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgZGJoYGhqZGFo6GxsSpAgD-IClY |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
ExternalDocumentID | US2024101528A1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_US2024101528A13 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 12:56:44 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_US2024101528A13 |
Notes | Application Number: US202118256650 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240328&DB=EPODOC&CC=US&NR=2024101528A1 |
ParticipantIDs | epo_espacenet_US2024101528A1 |
PublicationCentury | 2000 |
PublicationDate | 20240328 |
PublicationDateYYYYMMDD | 2024-03-28 |
PublicationDate_xml | – month: 03 year: 2024 text: 20240328 day: 28 |
PublicationDecade | 2020 |
PublicationYear | 2024 |
RelatedCompanies | BAYER AKTIENGESELLSCHAFT |
RelatedCompanies_xml | – name: BAYER AKTIENGESELLSCHAFT |
Score | 3.5276854 |
Snippet | The invention relates to substituted pyrazolo piperidine carboxylic acids, their salts and to processes for their preparation, and also to their use for... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | SUBSTITUTED PYRAZOLO PIPERIDINE CARBOXYLIC ACIDS |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240328&DB=EPODOC&locale=&CC=US&NR=2024101528A1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEB5KFfWmVbFaJaDkFixJk2wOQZJNQiNtEvKQ1kvJEwRJi434950sqfbU2z5g9sHOzvftzs4CPGlaqY5JmgsFkSRhooqZQAokrqVEyhQhsyiyi_a5p0yTyetCXvTgc_cWhsUJ_WHBEVGjctT3hu3Xm_9DLIv5Vm6fsw8sWr84sW7xHTtug8uJhLdM3Q58y6c8pXoS8V7I6nD1ySIxkCsdtUC6jbRvv5ntu5TNvlFxzuE4QHl1cwG9sh7AKd39vTaAk3l35Y3JTvu2lzCOEjOK3TjB3YYLlqHx7s98LnADJGOW69kcNULTXyxnLuUM6lrRFTw6dkynAja9-hvpKon2-yldQ79e1-UNcFKFVDKtUlXJFYRQWpoh8iqKsVZlhYxKOoTRIUm3h6vv4KzNtq5VIhlBv_n6Lu_R1jbZA5uiXwDPfMo |
link.rule.ids | 230,309,786,891,25594,76906 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LT4NAEJ401VhvWjU-qpJouBEbKLAciIEFUpQCKWBaLw0USEwMbSzGv--wodpTb5udZPaRnce3OzML8KhphTok6VLIiSQJI1XMBJIjcC0kUqToMosie2if-Mo4Gb3M5FkHPre5MKxO6A8rjogStUR5r5m-Xv9fYlkstnLzlH1g1-rZiXWLb9FxU1xOJLxl6nYYWAHlKdWTiPenjIanTxaJgVjpQG3q8zbO05vZ5KWsd42KcwKHIfKr6lPoFFUfenT791ofjibtkzc2W-nbnMEwSswoduMEtQ0XzqfGe-AFXOiGCMYs17c5akzNYDb3XMoZ1LWic3hw7JiOBRx68bfSRRLtzlO6gG61qopL4KQSoWRapqqyVNCF0tIMPa88H2pllssopFcw2Mfpej_5HnrjeOItPNd_vYHjhtSEWYlkAN3667u4RbtbZ3dsu34B_tR_tw |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=SUBSTITUTED+PYRAZOLO+PIPERIDINE+CARBOXYLIC+ACIDS&rft.inventor=SANDNER%2C+Peter&rft.inventor=WEBSTER%2C+Robert+Alan&rft.inventor=STELLFELD%2C+Timo&rft.inventor=BOULTADAKIS-ARAPINIS%2C+Melissa&rft.inventor=MATHAR%2C+Ilka&rft.inventor=COLLIN-KR%C3%96PELIN%2C+Marie-Pierre&rft.inventor=HOFMEISTER%2C+Lucas+Hudson&rft.inventor=DIETZ%2C+Lisa&rft.inventor=SCHMECK%2C+Carsten&rft.inventor=WUNDER%2C+Frank&rft.inventor=DIESKAU%2C+Andre&rft.inventor=CANDISH%2C+Lisa&rft.inventor=VAKALOPOULOS%2C+Alexandros&rft.inventor=ORTEGA+HERNANDEZ%2C+Nuria&rft.date=2024-03-28&rft.externalDBID=A1&rft.externalDocID=US2024101528A1 |