LARGE SCALE BIOREACTOR SYSTEM AND METHOD

A large scale bioreactor system includes a stainless steel large scale bioreactor having at least one valve assembly, and an aseptic connector assembly coupled to the at least one valve assembly of the bioreactor. A perfusion device includes an Alternating Tangential Filtration assembly with an auto...

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Main Authors Kaltenbrunner, Oliver, Sawicky, Thomsen P, Stimpfl, Gregory S, Choi, Min Kyu, Ranney, Jeffrey T, Roseland, John C, Hogenson, David C, Brothers, Mark O
Format Patent
LanguageEnglish
Published 07.03.2024
Subjects
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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Abstract A large scale bioreactor system includes a stainless steel large scale bioreactor having at least one valve assembly, and an aseptic connector assembly coupled to the at least one valve assembly of the bioreactor. A perfusion device includes an Alternating Tangential Filtration assembly with an autoclaved valve assembly coupled to the aseptic connector assembly, and the aseptic connector assembly includes one of a triclamp aseptic connector or a hose assembly. Single use feed containers include an aseptic connector assembly.
AbstractList A large scale bioreactor system includes a stainless steel large scale bioreactor having at least one valve assembly, and an aseptic connector assembly coupled to the at least one valve assembly of the bioreactor. A perfusion device includes an Alternating Tangential Filtration assembly with an autoclaved valve assembly coupled to the aseptic connector assembly, and the aseptic connector assembly includes one of a triclamp aseptic connector or a hose assembly. Single use feed containers include an aseptic connector assembly.
Author Choi, Min Kyu
Kaltenbrunner, Oliver
Stimpfl, Gregory S
Hogenson, David C
Sawicky, Thomsen P
Brothers, Mark O
Roseland, John C
Ranney, Jeffrey T
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– fullname: Stimpfl, Gregory S
– fullname: Choi, Min Kyu
– fullname: Ranney, Jeffrey T
– fullname: Roseland, John C
– fullname: Hogenson, David C
– fullname: Brothers, Mark O
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SubjectTerms APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
Title LARGE SCALE BIOREACTOR SYSTEM AND METHOD
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