ANTIBODY-DRUG CONJUGATES COMPRISING A CYCLIC DINUCLEOTIDE

The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases.The present disclosure relates to a compound represented by the formula (I):wherein each symbol is as defined in the...

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Main Authors SEKI, TOMOHIRO, SHIOKAWA, ZENYU, TOMINARI, YUSUKE, SHIBUYA, AKITO, MOCHIZUKI, MICHIYO, NAKAGAWA, YASUO, MURATA, SHUMPEI, NAKAYAMA, YAYOI, OKABE, ATSUTOSHI, SASAKI, YUSUKE, FREEZE, BRIAN SCOTT, GREENSPAN, PAUL D, KATO, TAISUKE, HIDAKA, KOSUKE, NAKADA, YOSHIHISA, SAITOH, MORIHISA, OKANIWA, MASANORI, SETO, MASAKI, YOSHIKAWA, MASATO, ODA, TSUNEO, TAWARAISHI, TAISUKE, WADA, YASUFUMI
Format Patent
LanguageEnglish
Published 29.02.2024
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SUGARS
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Summary:The present disclosure provides a compound having a STING agonistic activity, which may be expected to be useful as an agent for the prophylaxis or treatment of STING-related diseases.The present disclosure relates to a compound represented by the formula (I):wherein each symbol is as defined in the description, or a salt thereof.
Bibliography:Application Number: US202318310467