FLUIDIC DEVICES WITH REACTANT INJECTION

• Main Authors: Haines, Paul Mark, Lahmann, John Michael, Faase, Kenneth James
• Format: Patent
• Language: English
• Published: 25.01.2024
• Subjects: CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; TRANSPORTING

A fluidic device can include interconnected volumes including a bulk fluid volume fluidically connected in series with a capillary volume to receive a density gradient column, a reservoir of a reconstitution buffer positioned outside the interconnected volumes, and a buffer inlet chamber to receive reconstitution buffer from the reservoir of reconstitution buffer. The fluidic device can also include a reactant chamber connected to the buffer inlet chamber by a fluid channel, wherein the reactant chamber contains a reactant, and a reactant injection channel connecting the reactant chamber to the capillary volume to inject the reconstitution buffer and reactant into the capillary volume.