SERUM-FREE MEDIUM FOR DIFFERENTIATION OF A PROGENITOR CELL

The invention relates inter alia to a method for differentiating a muscle progenitor cell, comprising the step of: -culturing a muscle progenitor cell in a serum-free medium for differentiating a muscle progenitor cell, wherein said serum-free medium comprises -at least one differentiation inducer s...

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Main Authors MEßMER, Tobias, CRUZ, Helder, KLEVERNIC, Iva, MELZENER, Lea, VAN ESSEN, Anon, FURQUIM, Carolina, FLACK, Joshua Edwin, POST, Mark
Format Patent
LanguageEnglish
Published 11.01.2024
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Summary:The invention relates inter alia to a method for differentiating a muscle progenitor cell, comprising the step of: -culturing a muscle progenitor cell in a serum-free medium for differentiating a muscle progenitor cell, wherein said serum-free medium comprises -at least one differentiation inducer selected from the group consisting of a lysophosphatidic acid receptor 1 (LPAR1) agonist, a lysophosphatidic acid receptor 3 (LPAR3) agonist, an oxytocin receptor (OXTR) agonist, a glucagon receptor (GCGR) agonist, a lactate and a Notch signaling pathway inhibitor.
Bibliography:Application Number: US202118254264