Method for the Production of Thiocarbamate Derivatives A2AR Inhibitors
The present disclosure relates to synthesis of enantiomerically rich key drug intermediates as a means for manufacturing of thiocarbamate derivatives as A2A adenosine receptor (A2AR) inhibitors. More particularly, the present disclosure provides a viable efficient technology using enzymatic biotrans...
Saved in:
| Main Authors | , , , |
|---|---|
| Format | Patent |
| Language | English |
| Published |
21.12.2023
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | The present disclosure relates to synthesis of enantiomerically rich key drug intermediates as a means for manufacturing of thiocarbamate derivatives as A2A adenosine receptor (A2AR) inhibitors. More particularly, the present disclosure provides a viable efficient technology using enzymatic biotransformation process which utilizes cheaper substrate for production of high value key intermediates for A2AR inhibitors. |
|---|---|
| AbstractList | The present disclosure relates to synthesis of enantiomerically rich key drug intermediates as a means for manufacturing of thiocarbamate derivatives as A2A adenosine receptor (A2AR) inhibitors. More particularly, the present disclosure provides a viable efficient technology using enzymatic biotransformation process which utilizes cheaper substrate for production of high value key intermediates for A2AR inhibitors. |
| Author | Deligny, Michael Jiang, Xiangjun Crosignani, Stefano Jiao, Xuecheng |
| Author_xml | – fullname: Deligny, Michael – fullname: Jiao, Xuecheng – fullname: Jiang, Xiangjun – fullname: Crosignani, Stefano |
| BookMark | eNqNyr0KwjAQAOAMOvj3DgfOQk0rzkEtOgiidS7X9EICmivJ2ed38QGcvuWbq0nkSDNVX0k89-A4gXiCW-L-YyVwBHbQ-MAWU4dvFIIjpTCihJEyGG3ucIk-dEE45aWaOnxlWv1cqHV9ag7nDQ3cUh7QUiRpnw9d6LIq9uVOm2353_oC0YQ1lw |
| ContentType | Patent |
| DBID | EVB |
| DatabaseName | esp@cenet |
| DatabaseTitleList | |
| Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Chemistry Sciences |
| ExternalDocumentID | US2023407352A1 |
| GroupedDBID | EVB |
| ID | FETCH-epo_espacenet_US2023407352A13 |
| IEDL.DBID | EVB |
| IngestDate | Fri Jul 19 12:56:55 EDT 2024 |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | false |
| Language | English |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-epo_espacenet_US2023407352A13 |
| Notes | Application Number: US202118034449 |
| OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231221&DB=EPODOC&CC=US&NR=2023407352A1 |
| ParticipantIDs | epo_espacenet_US2023407352A1 |
| PublicationCentury | 2000 |
| PublicationDate | 20231221 |
| PublicationDateYYYYMMDD | 2023-12-21 |
| PublicationDate_xml | – month: 12 year: 2023 text: 20231221 day: 21 |
| PublicationDecade | 2020 |
| PublicationYear | 2023 |
| RelatedCompanies | iTeos Belgium SA |
| RelatedCompanies_xml | – name: iTeos Belgium SA |
| Score | 3.5084856 |
| Snippet | The present disclosure relates to synthesis of enantiomerically rich key drug intermediates as a means for manufacturing of thiocarbamate derivatives as A2A... |
| SourceID | epo |
| SourceType | Open Access Repository |
| SubjectTerms | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| Title | Method for the Production of Thiocarbamate Derivatives A2AR Inhibitors |
| URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231221&DB=EPODOC&locale=&CC=US&NR=2023407352A1 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dS8MwED_GFPVNp-LHlIDSt-LSptt8KNK1K1PoNrZW9jaSNmUF6cZW9d_3Gjvd097yAeEScrnfL8ndATzyVlfQGEkOFYzrjElTFx2a6ImVpNwUJrXUi2kwbA8i9jazZjX42PrCqDih3yo4ImpUjPpeqPN69X-J5am_lZsnkWHT8sUPbU-r2DGCFcOgmtez--ORN3I117WjqTacqD7kLgg3HORKBwikO6U-9N97pV_Kateo-KdwOMbx8uIMajJvwLG7zb3WgKOgevLGYqV9m3PwA5XumSDOJIjbyPg3WisKS5YpCRcZ2qW14IhBJfFwZ32poN4b4hjOhLzmi0xkZW6dC3jw-6E70FGg-d_859F0V3rzEur5MpdXQBhL0jaTIhbPvCQqXMbtbsyRkSSihTjhGpr7RrrZ330LJ2W1_Lth0CbUi_WnvEMLXIh7tXA_Y5aJ7g |
| link.rule.ids | 230,309,783,888,25576,76876 |
| linkProvider | European Patent Office |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3fT8IwEL4QNOKbosYfqE00e1tkWwf4QAxsLEPZWGAY3ki7lbDEbASm_vveKihPvDW9pLk2vd73tdc7gEdWb3EtQpKjccpUSoWh8qYWq7EZz5nBDc2UL6ae33An9HVqTkvwsf0LI_OEfsvkiGhREdp7Ls_r5f8lli1jK9dPPMGu7MUJ27ayYccIVnRdU-xuuxcM7aGlWFZ7Mlb8kZQhd0G40UGudIAgu1nYQ--9W_xLWe46FecEDgMcL81PoSTSKlSsbe21Khx5mydvbG6sb30GjifLPRPEmQRxGwl-s7WisiSbk3CRoF9acYYYVBAbd9aXTOq9Jh29MyL9dJHwpKitcw4PTi-0XBUVmv3NfzYZ72pvXEA5zVJxCYTSeN6ggkf8mRVEhYmo0YoYMpKY1xEnXEFt30jX-8X3UHFDbzAb9P23GzguREUch67VoJyvPsUteuOc38lF_AEH2ozh |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=Method+for+the+Production+of+Thiocarbamate+Derivatives+A2AR+Inhibitors&rft.inventor=Deligny%2C+Michael&rft.inventor=Jiao%2C+Xuecheng&rft.inventor=Jiang%2C+Xiangjun&rft.inventor=Crosignani%2C+Stefano&rft.date=2023-12-21&rft.externalDBID=A1&rft.externalDocID=US2023407352A1 |