STABILIZED INTRAOCULAR DRUG DELIVERY SYSTEMS AND METHODS OF USE

Embodiments disclosed herein generally relate to an intraocular drug delivery system configured for implantation into an eye of a subject. The intraocular drug delivery system can include an intraocular lens (IOL) and a drug delivery component. The IOL includes an anterior side, a posterior side opp...

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Main Authors Sussman, Glenn R, Kahook, Malik Y, Cable, II, Craig Alan, Maass, Sean
Format Patent
LanguageEnglish
Published 21.12.2023
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Abstract Embodiments disclosed herein generally relate to an intraocular drug delivery system configured for implantation into an eye of a subject. The intraocular drug delivery system can include an intraocular lens (IOL) and a drug delivery component. The IOL includes an anterior side, a posterior side opposite the anterior side, a lens bordered by an edge and a haptic extending outwardly from the edge of the lens at a lens-haptic junction. The haptic includes, at the lens-haptic junction, a relief cut on the posterior side of the IOL. The drug delivery component includes a therapeutic agent and a fixation portion having an opening configured to receive the haptic therethrough. The fixation portion is configured to be secured to the relief cut of the haptic such that outward movement of the drug delivery component relative to the lens is inhibited.
AbstractList Embodiments disclosed herein generally relate to an intraocular drug delivery system configured for implantation into an eye of a subject. The intraocular drug delivery system can include an intraocular lens (IOL) and a drug delivery component. The IOL includes an anterior side, a posterior side opposite the anterior side, a lens bordered by an edge and a haptic extending outwardly from the edge of the lens at a lens-haptic junction. The haptic includes, at the lens-haptic junction, a relief cut on the posterior side of the IOL. The drug delivery component includes a therapeutic agent and a fixation portion having an opening configured to receive the haptic therethrough. The fixation portion is configured to be secured to the relief cut of the haptic such that outward movement of the drug delivery component relative to the lens is inhibited.
Author Kahook, Malik Y
Cable, II, Craig Alan
Sussman, Glenn R
Maass, Sean
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RelatedCompanies SpyGlass Pharma, Inc
The Regents of the University of Colorado, A body corporate
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Snippet Embodiments disclosed herein generally relate to an intraocular drug delivery system configured for implantation into an eye of a subject. The intraocular drug...
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SourceType Open Access Repository
SubjectTerms BANDAGES, DRESSINGS OR ABSORBENT PADS
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROSTHESES
TREATMENT OR PROTECTION OF EYES OR EARS
Title STABILIZED INTRAOCULAR DRUG DELIVERY SYSTEMS AND METHODS OF USE
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