BENZAZEPINE DERIVATIVES

The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof.In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is -C(═O)-NH-, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hyd...

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Main Authors YAMABE, Hokuto, URUSHIMA, Tatsuya, TAKUWA, Masatoshi, TANAKA, Hirotaka, FUJIWARA, Hideto, FUJITA, Shigekazu, HANARI, Taiki, KAN, Keizo, MATSUDA, Satoshi, OHDACHI, Kazuhiro, MENJO, Yasuhiro
Format Patent
LanguageEnglish
Published 24.08.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof.In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is -C(═O)-NH-, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
AbstractList The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses thereof.In the formula, R1 is optionally substituted C1-6 alkyl, etc.; L is -C(═O)-NH-, etc.; Ring A1 is a hydrocarbon ring, etc.; Ring A2 is a hydrocarbon ring, etc.; and each of Rings A1 and A2 may have at least one substituent.
Author TAKUWA, Masatoshi
FUJIWARA, Hideto
OHDACHI, Kazuhiro
KAN, Keizo
HANARI, Taiki
MENJO, Yasuhiro
YAMABE, Hokuto
TANAKA, Hirotaka
MATSUDA, Satoshi
URUSHIMA, Tatsuya
FUJITA, Shigekazu
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– fullname: URUSHIMA, Tatsuya
– fullname: TAKUWA, Masatoshi
– fullname: TANAKA, Hirotaka
– fullname: FUJIWARA, Hideto
– fullname: FUJITA, Shigekazu
– fullname: HANARI, Taiki
– fullname: KAN, Keizo
– fullname: MATSUDA, Satoshi
– fullname: OHDACHI, Kazuhiro
– fullname: MENJO, Yasuhiro
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Snippet The present invention provides novel benzazepine compounds of Formula (1), or salts thereof, having vasopressin V1a and V2 antagonisms, and medical uses...
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HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title BENZAZEPINE DERIVATIVES
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