POLYMORPHS OF SELINEXOR
The present invention relates to crystalline forms of the compound represented by Structural Formula I, and compositions comprising crystalline forms of the compound represented by Structural Formula I described herein. The crystalline forms of the compound of Structural Formula I and compositions c...
Saved in:
Main Authors | , |
---|---|
Format | Patent |
Language | English |
Published |
03.08.2023
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The present invention relates to crystalline forms of the compound represented by Structural Formula I, and compositions comprising crystalline forms of the compound represented by Structural Formula I described herein. The crystalline forms of the compound of Structural Formula I and compositions comprising the crystalline forms of the compound of Structural Formula I provided herein, in particular, single crystalline Form A, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders associated with CRM1 activity, including cancer. Also described herein are methods for preparing the compound of Structural Formula I and its single crystalline forms. |
---|---|
AbstractList | The present invention relates to crystalline forms of the compound represented by Structural Formula I, and compositions comprising crystalline forms of the compound represented by Structural Formula I described herein. The crystalline forms of the compound of Structural Formula I and compositions comprising the crystalline forms of the compound of Structural Formula I provided herein, in particular, single crystalline Form A, can be incorporated into pharmaceutical compositions, which can be used to treat various disorders associated with CRM1 activity, including cancer. Also described herein are methods for preparing the compound of Structural Formula I and its single crystalline forms. |
Author | Austad, Brian C Roe, David G |
Author_xml | – fullname: Austad, Brian C – fullname: Roe, David G |
BookMark | eNrjYmDJy89L5WQQD_D3ifT1DwrwCFbwd1MIdvXx9HON8A_iYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBkbGRiZGpobmjobGxKkCAD6pIlM |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
ExternalDocumentID | US2023242517A1 |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_US2023242517A13 |
IEDL.DBID | EVB |
IngestDate | Fri Oct 11 05:31:34 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | English |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_US2023242517A13 |
Notes | Application Number: US202318132241 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230803&DB=EPODOC&CC=US&NR=2023242517A1 |
ParticipantIDs | epo_espacenet_US2023242517A1 |
PublicationCentury | 2000 |
PublicationDate | 20230803 |
PublicationDateYYYYMMDD | 2023-08-03 |
PublicationDate_xml | – month: 08 year: 2023 text: 20230803 day: 03 |
PublicationDecade | 2020 |
PublicationYear | 2023 |
RelatedCompanies | Karyopharm Therapeutics Inc |
RelatedCompanies_xml | – name: Karyopharm Therapeutics Inc |
Score | 3.4886003 |
Snippet | The present invention relates to crystalline forms of the compound represented by Structural Formula I, and compositions comprising crystalline forms of the... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | POLYMORPHS OF SELINEXOR |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230803&DB=EPODOC&locale=&CC=US&NR=2023242517A1 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMQMttTA2SNE1MEuz0AVWARa6icaJZsCMl2xoDKwODM1TwQtk_cw8Qk28IkwjmBhyYHthwOeEloMPRwTmqGRgfi8Bl9cFiEEsF_DaymL9pEygUL69W4itixq0dwxsT1sYGKu5ONm6Bvi7-DurOTvbhgar-QWB5UCta0NzR2BfiRXYkDYHLQBzDXMC7UspQK5U3AQZ2AKA5uWVCDEwpeYJM3A6w-5eE2bg8IVOeQOZ0NxXLMIgHuDvE-nrHxTgEazg76YQ7Orj6eca4R8kyqDs5hri7KELtCEe7qH40GBk5xiLMbAAu_qpEgwKFqlpZpZmyebGJikmJqlG5olpyUnAKjjVJC3JEliPpEoyyOAzSQq_tDQDF4gLXr5mLMPAUlJUmioLrFJLkuTAIQEA6FV1ag |
link.rule.ids | 230,309,783,888,25578,76884 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1LS8NAEB5KFetN69uqASW3YOrGTXoIYvMgal7kIfEUknQDgtRiI_59J0uqPfW27MDsA2a_md1vZgFuaEu1IPJMkmmtSQgBmlSQgqLhVWOCcDBWGSfI-tRJlefsPuvBxyoXhtcJ_eHFEdGiKrT3hp_Xi_9LLJNzK5e35Tt2fT7YiW6KXXSM_rQmE9Gc6lYYmIEhGoaexqIfcVnrXY_VR4yVttDJ1tpK-9brtM1LWayDir0H2yHqmzf70GPzIQyM1d9rQ9jxuidvbHbWtzyA4zBw37wgCp1YCGwhttwn38qC6BCubSsxHAlHyP8WlKfx-nTIEfQx1GcnIGisphNaqUSZKQq7U4u6KhGCmVKXE8QRdgqjTZrONouvYOAknpvj5F7OYbcVcSobGUG_-fpmFwivTXnJd-UXkSF4Wg |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=POLYMORPHS+OF+SELINEXOR&rft.inventor=Austad%2C+Brian+C&rft.inventor=Roe%2C+David+G&rft.date=2023-08-03&rft.externalDBID=A1&rft.externalDocID=US2023242517A1 |