A UNIVERSAL ADOPTIVE IMMUNOTHERAPY APPROACH TO TREAT COVID-19 AND FUTURE EMERGING INFECTIOUS DISEASES

• Main Authors: CULLEY, Brian M, BINETTE, Francois, SKALITER, Rami
• Format: Patent
• Language: English
• Published: 06.07.2023
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

Provided herein are methods and compositions for engineering antigen-presenting cells (APCs), such as dendritic cells (DCs), macrophages, and B-Cells, that are modified to express viral antigens. With this approach, large cell banks can be created that can be rapidly modified and deployed to fight v...