7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF

7H-Pyrrolo[2,3-d]pyrimidine compound for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of 7H-pyrrolo[2,3-d]pyrimidine compounds or analogs thereof, in the treatment of disorders characterized by overexpression of DYRK1A (e.g., can...

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Main Authors KC, Sunil Kumar, Vakiti, Ramkrishna Reddy, Chiruta, Chandramouli, Hofilena, Brian Joseph, Eastman, Brian Walter, Marakovits, Joseph Timothy, Mittapalli, Gopi Kumar, Turner, Lewis Daniel, Mak, Chi Ching
Format Patent
LanguageEnglish
Published 01.06.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Abstract 7H-Pyrrolo[2,3-d]pyrimidine compound for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of 7H-pyrrolo[2,3-d]pyrimidine compounds or analogs thereof, in the treatment of disorders characterized by overexpression of DYRK1A (e.g., cancer, Down syndrome, Alzheimer's disease, diabetes, viral infections, and osteoarthritis).
AbstractList 7H-Pyrrolo[2,3-d]pyrimidine compound for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of 7H-pyrrolo[2,3-d]pyrimidine compounds or analogs thereof, in the treatment of disorders characterized by overexpression of DYRK1A (e.g., cancer, Down syndrome, Alzheimer's disease, diabetes, viral infections, and osteoarthritis).
Author Eastman, Brian Walter
Chiruta, Chandramouli
Mak, Chi Ching
Vakiti, Ramkrishna Reddy
Mittapalli, Gopi Kumar
Turner, Lewis Daniel
KC, Sunil Kumar
Hofilena, Brian Joseph
Marakovits, Joseph Timothy
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– fullname: Eastman, Brian Walter
– fullname: Marakovits, Joseph Timothy
– fullname: Mittapalli, Gopi Kumar
– fullname: Turner, Lewis Daniel
– fullname: Mak, Chi Ching
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Snippet 7H-Pyrrolo[2,3-d]pyrimidine compound for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Title 7H-PYRROLO[2,3-D]PYRIMIDINES AND PREPARATION AND USES THEREOF
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