ALPHA SUBSTITUTED STAT INHIBITORS AND COMPOSITIONS THEREOF

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for e...

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Bibliographic Details
Main Authors FLECK, Roman, KRASKOUSKAYA, Dziyana, PROUDFOOT, John, PALERM, Angel Sampedro, DARWISH, Alla, OMEARA, Jeff, GUNNING, Patrick Thomas
Format Patent
LanguageEnglish
Published 04.05.2023
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as, for example, breast cancer and pancreatic cancer.
Bibliography:Application Number: US202117909179